enteroaggregative escherichia coli, a heterogenous, underestimated and under-diagnosed e. coli pathotype in iran

نویسندگان

anis jafari

mohammad mehdi aslani

saeid bouzari phd

چکیده

the main features of enteroaggregative escherichia coli (eaec) pathogenesis include attachment of bacteria to the intestinal mucosa, production of various toxins and cytotoxins, and stimulation of mucosal inflammation. ‘virulence’ genes encode these features. comparison of different eaec isolates has shown that the virulence gene content of these isolates varies considerably. the heterogeneity of eaec strains was concluded from the results obtained from the volunteer as well as other studies. although the underlying mechanism behind the apparent increase in o104:h4 virulence is not known, several bacterial factors have been implicated. in this review, the known virulence factors involved in pathogenesis of eaec pathotype are summarized.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Enteroaggregative Escherichia coli, a heterogenous, underestimated and under-diagnosed E. coli pathotype in Iran

The main features of enteroaggregative Escherichia coli (EAEC) pathogenesis include attachment of bacteria to the intestinal mucosa, production of various toxins and cytotoxins, and stimulation of mucosal inflammation. 'Virulence' genes encode these features. Comparison of different EAEC isolates has shown that the virulence gene content of these isolates varies considerably. The heterogeneity ...

متن کامل

Enteroaggregative Escherichia Coli (EAEC) in South of Iran

Introduction:  The aim of the present study was to investigate the presence and the frequency of EAEC as etiologic agent of diarrhea in Shiraz. Enteroaggregative E. coli (EAEC) is increasingly recognized as a cause of often persistent diarrhoea in children and adults in both developing and developed countries, and have been identified as the cause of several outbreaks worldwide.   Materials and...

متن کامل

Enteroaggregative Escherichia coli.

Enteroaggregative Escherichia coli (EAEC) are an increasingly important cause of diarrhoea. E. coli belonging to this category cause watery diarrhoea, which is often persistent and can be inflammatory. EAEC have been implicated in sporadic diarrhoea in children and adults, in both developing and developed countries, and have been identified as the cause of several outbreaks worldwide. EAEC are ...

متن کامل

The Prevalence of Enteroaggregative Escherichia coli in cases of Diarrhea in Gorgan, IRAN

Abstract Background and objectives: Diarrhea is one of the main cases of morbidity and mortality among children in developing countries. Enteroaggregative Escherichia coli (EAggEC) is an emerging diarrheal pathogen that has been associated characteristically with persistent diarrhea among infants, particularly in the developing Counties. Therefore, we decided to study the prevalence of enteroag...

متن کامل

Enteroaggregative Escherichia coli: epidemiology, virulence and detection.

Enteroaggregative Escherichia coli (EAEC) is a subgroup of diarrhoeagenic E. coli (DEC) that during the past decade has received increasing attention as a cause of watery diarrhoea, which is often persistent. EAEC have been isolated from children and adults worldwide. As well as sporadic cases, outbreaks of EAEC-caused diarrhoea have been described. The definition of EAEC is the ability of the ...

متن کامل

Evaluation of Prevalence, Homology and Immunogenicity of Dispersin among Enteroaggregative Escherichia coli Isolates from Iran

Background: Diarrhea, caused by enteroaggregative Escherichia coli (EAEC), is an important cause of illness and death. Numerous virulent factors have been described in EAEC. However, their prevalence was highly variable among EAECs of distinct geographic locations. Studies have shown that dispersin (antiaggregation protein, aap) is one of the important and abundant virulent factors in EAEC. In ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
gastroenterology and hepatology from bed to bench

جلد ۶، شماره ۲، صفحات ۲۰۱۳-۶

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023